The compound is synthesized through a multi-step organic process involving selective alkylation of a 2'-deoxyribose scaffold, followed by azido group modifications to enhance binding affinity. Structural characterization confirms its thermal stability and solubility profile suitable for in vitro testing.

Fri, 08 May 2026 10:41:05 +0000

Title: Advances in Nucleic Acid Analog Synthesis: Dual Alkylation and Azido Modification Enhance Binding Affinity and Functional Stability Meta Description: Explore the synthesis of a novel nucleic acid analog featuring selective alkylation of a 2'-deoxyribose scaffold and azido group modifications. Learn how these chemical strategies improve binding affinity, thermal stability, and solubility for robust in vitro applications. --- ### Introduction to Nucleic Acid Analog Development